Talk Python to Me is a weekly podcast hosted by developer and entrepreneur Michael Kennedy. We dive deep into the popular packages and software developers, data scientists, and incredible hobbyists doing amazing things with Python. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from the leaders. And if you've been Pythoning for years, you'll learn about your favorite packages and the hot new ones coming out of open source.

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Title Date published
#512: Building a JIT Compiler for CPython 2025-07-02
#511: From Notebooks to Production Data Science Systems 2025-06-25
#510: 10 Polars Tools and Techniques To Level Up Your Data Science 2025-06-18
#509: GPU Programming in Pure Python 2025-06-11
#508: Program Your Own Computer with Python 2025-06-06
#507: Agentic AI Workflows with LangGraph 2025-06-02
#506: ty: Astral's New Type Checker (Formerly Red-Knot) 2025-05-19
#505: t-strings in Python (PEP 750) 2025-05-13
#504: Developer Trends in 2025 2025-05-05
#503: The PyArrow Revolution 2025-04-28
#502: Django Ledger: Accounting with Python 2025-04-21
#501: Marimo - Reactive Notebooks for Python 2025-04-14
#500: Django Simple Deploy and other DevOps Things 2025-04-10
#499: BeeWare and the State of Python on Mobile 2025-03-31
#498: Algorithms for high performance terminal apps 2025-03-24
#497: Outlier Detection with Python 2025-03-21
#496: Scaf: Complete blueprint for new Python Kubernetes projects 2025-03-14
#495: OSMnx: Python and OpenStreetMap 2025-02-24
#494: Update on Flet: Python + Flutter UIs 2025-02-21
#493: Quarto: Open-source technical publishing 2025-02-09
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